The Seahawks take on the 49ers at Lumen Field in Week 5, with kick-off at 7:25am AEDT on Monday 12 October. Here’s our Seahawks vs 49ers prediction and the best odds at Neds before you bet.
This is my game of the week and I am backing the over. Sam Darnold is back from the glute injury he picked up in Week 1 and is not on this week’s injury report, so he plays.
Two good teams, points on the board, give me all of it.
Seahawks vs 49ers Odds & Popular Betting Markets
Here’s a quick look at the current odds and popular betting markets for the Seahawks vs 49ers matchup.
*odds are correct at the time of publishing and are subject to change
| Team | Odds | |
|---|---|---|
| San Francisco 49ers (3) | 1.96 | Bet Now |
| Seattle Seahawks (-3) | 1.85 | Bet Now |
NFL odds correct as of 08/10/2026 and subject to change. Event scheduled to start at 12/10/2026 6:25am AEST.
NFL odds correct as of 08/10/2026 and subject to change. Event scheduled to start at 12/10/2026 6:25am AEST.