Got a bet in mind for Cardinals vs Lions? Check our prediction and tips first. They meet at State Farm Stadium on Monday 12 October at 7:25am AEDT.
I don’t think the Lions are that good this year and their pass defence is the worst in the league, full stop. They’re giving up 304 passing yards a game, and last week Bryce Young threw for 329 while Tet McMillan had 192 yards for Carolina.
So I think Brissett and the Cardinals can do some damage. Do I think Arizona are good enough to actually win? No. But Michael Wilson should rack up yards against this secondary.
Cardinals vs Lions Odds & Popular Betting Markets
Here’s a quick look at the current odds and popular betting markets for the Cardinals vs Lions matchup.
*odds are correct at the time of publishing and are subject to change
| Team | Odds | |
|---|---|---|
| Detroit Lions (-5.5) | 1.92 | Bet Now |
| Arizona Cardinals (5.5) | 1.88 | Bet Now |
NFL odds correct as of 08/10/2026 and subject to change. Event scheduled to start at 12/10/2026 6:25am AEST.
NFL odds correct as of 08/10/2026 and subject to change. Event scheduled to start at 12/10/2026 6:25am AEST.