The post Origin action starts with the Panthers travelling to Canberra for a difficult Friday night clash with the Raiders.
The Titans will need to find a way to notch a win against one of the form teams of the competition when they host South Sydney.
The Sea Eagles face a tough assignment against the Warriors and the Knights will be relying on Kalyn Ponga to pull off a surprise win against the Roosters.
The Sharks will battle the Tigers and Craig Bellamy will square off against Wayne Bennett when the Storm tackle the Broncos.
The action in the round finishes on Monday with the Bulldogs facing a tough assignment against the Dragons.
Both of these sides benefited from the bye in round thirteen and will be hoping their State of Origin players come through from the opening game at the MCG unscathed.
The Panthers will be welcoming back four players, including halves pairing Nathan Cleary and James Maloney.
The Raiders will be keeping an eye on the health of Origin forward Josh Papalii and have plenty of cover for the Queensland representative.
The Panthers are sitting in second spot on the NRL ladder and face a tough assignment to continue their streak. Canberra should enjoy the home clash on a cold and wet Friday night and look for Jarrod Croker to get on the scoresheet in a close win for the Green Machine.
The Rabbitohs will be without State of Origin winger Dane Gagai, who fractured his finger in preparation for the first Origin game for Queensland. South Sydney have been playing some champagne football to rocket into third place on the NRL ladder and will be keen to continue their outstanding form against a Gold Coast side low on form and confidence.
The Titans will be hoping to bring Jai Arrow and Jarrod Wallace back into the line-up after Origin, while the Rabbitohs will welcome back a number of key players including Greg Inglis.
While the Titans are languishing in 12th spot on the NRL ladder, they have shown some signs of improvement this season, but South Sydney should be able to come out on top in an entertaining clash.
The Sea Eagles found a way to lose to an improved Cowboys side last week and will face a difficult assignment against the Warriors.
New Zealand have made some massive strides forward this season and Blake Green will be relishing the opportunity to put on some points against his former side.
The Warriors will be buoyed by the return of halfback Shaun Johnson to their line-up and their players will be itching to get on the park, with none of the side involved in the State of Origin series.
The Sea Eagles have had the wood over the Warriors for some time, but New Zealand will be able to take advantage of Manly’s poor run of form to record a memorable win.
The Knights were able to record a memorable win in round 13, steamrolling Parramatta 30-4.
The Bondi outfit sits in sixth spot on the NRL ladder and will be welcoming back a number of stars from Origin duty. The Roosters have won nine of their last ten games against Newcastle, including a big 30-point win in round three.
Sydney have dominated Newcastle in the steel city and the Knights will be missing the experience of Mitchell Pearce in the halves. The Roosters should be able to continue their good form and maintain their dominance over Newcastle with a comfortable win.
Parramatta coach Brad Arthur must be counting the days until the end of the season as things don’t get any easier for his side with a clash against the Cowboys.
North Queensland were able to record a memorable win over the Sea Eagles last week and will be welcoming back Coen Hess, Michael Morgan and Gavin Cooper from Origin duty.
The Eels will be without Mitchell Moses, Will Smith and have question marks over the fitness of Bevan French. Both of these sides have been disappointing this season and the Cowboys should be able to get the better of the Eels with a fully fit Johnathan Thurston running the show at halfback.
The Sharks have survived some major dramas with injuries to some of their key players to remain inside the top eight. Cronulla were on the end of a major upset last week with the Rabbitohs getting the better of Cronulla without their Origin stars.
After their bright start to the season, the Wests Tigers have slipped out of the top eight, thanks to a 2-point loss to the Roosters in round 13.
The Tigers have been one of the big improvers of the competition under Ivan Cleary and will need to find a way to put some points on the board against a tough Cronulla defence. The Sharks will be looking to get back on the winner’s list and expect them to grind out a tough win in what should be an entertaining encounter.
The visit by the Broncos to Melbourne comes at an interesting time for both clubs. Rumours continue to swirl that Melbourne coach Craig Bellamy will inherit the clipboard at Red Hill.
Despite a horrible run with injuries the Broncos are hanging onto a spot in the top-eight and will be hoping to remain competitive against a Melbourne side that has only lost two games at home.
The Storm will be without fullback Billy Slater and the Broncos have struggled for direction in attack this season. The Storm should be too strong at home and should have little trouble recording a win against Brisbane.
The Dragons remain on top of the NRL ladder and will be looking to continue their outstanding run of form against the Bulldogs.
Canterbury are a club in crisis with a number of their stars set to leave the Bulldogs due to ongoing salary cap issues.
Bulldogs coach Dean Pay faces a tough task motivating his side against one of the form teams of the competition and will be hoping that half Kieran Foran can rediscover the type of form that made him one of the most damaging playmakers in the competition.